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What is 1P-LSD?
1P-LSD or 1-propionyl-lysergic acid diethylamide is a psychedelic drug of the lysergamide class that is a derivative and functional analogue of LSD and a homologue of ALD-52. It has been sold online as a designer drug since
1P-LSD itself is only mildly psychedelic. It has a 67-fold less binding affinity for the 5-HT1A receptors, 13-fold less activity at the 5-HT2A receptors, and a 3.5-fold increase at h5-HT2C receptors than LSD-25 .
However, 1P LSD is a prodrug for LSD, which means it’s converted to LSD by the liver, which then goes on to produce psychoactive effects.
1P-LSD is a novel semi-synthetic psychedelic substance of the lysergamide class. It is closely related to LSD and is reported to produce near-identical effects. The pharmacology is unknown. Nevertheless, it produces psychedelic effects by acting on serotonin receptors in the brain.
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The original synthesis date of this product is unknown. Unlike most research chemicals, 1P LSD has no prior record in the scientific literature. The first reports use surfaced in 2015 following its appearance on the online research chemical market.
It has been sold online as a designer drug since 2015
The effects profile of it is not well defined in the scientific literature. It is generally thought to be comparable to that of LSD. Many anecdotal reports indicate that it has a slightly shorter duration than LSD in humans, with the majority of users stating that they cannot distinguish the qualitative effects from LSD.
1P LSD For Sale: Specs & Technical Details
|Active Ingredient||1-propionyl-lysergic acid diethylamide|
|Level of Risk||Low|
|Other Names||Legal Acid|
|Most Common Side-Effects||Anxiety & paranoia|
|Duration of Effects||7 – 11 hours|
|Legality||Not Scheduled In Most Countries (Legal Grey-Area)|
What’s The Dose of 1P LSD?
The dose of 1P-LSD is equivalent to LSD. There have never been any studies on the effective dose of 1P LSD.
- Microdose — 10–20 micrograms
- Threshold Dose — 25–40 micrograms
- Standard Psychoactive Dose — 80–200 micrograms
- Heroic Dose — 200–400 micrograms
What Does 1P-LSD Feel Like?
The effects of 1P LSD are virtually identical to that of LSD. The only difference is that it can take a little bit longer for the effects to kick in. This is because the it needs to first be metabolized by the liver and turned into LSD.
The experience can vary widely depending on your internal mental state. If you’re depressed or anxious going into the experience, 1P-LSD is going to inflate this even further. Likewise, if you feel excited, positive, and curious, 1P LSD is going to expand this state of consciousness even further.
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This is exactly why the concept of set (mindset) and setting (the environment and people you’re with during the trip) is so important. Going into the experience with a negative attitude, which can include fear, anxiety, or depression, will ultimately lead to a more challenging experience and may even pose psychological harm.
The positive effects of 1P LSD:
- Remembrance of significant life events
- Mystical experiences
- Cathartic experiences
- Deep-reaching insightful experiences
- A strong sense of awe & wonder
- Altered perception of time
negative effects of 1P-LSD:
- Reliving past traumatic experiences
- Believing people are “out to get you”
- Confusion and frustration when performing routine tasks
- Triggering of psychosis or other mental illness
Is 1P LSD Legal?
Technically, 1P-LSD isn’t listed as a controlled substance in either Canada or the United States.
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In both countries, you can order this substance from various sources online. In Canada, it’s very unlikely to experience any legal troubles for being in possession of this substance. However, there have yet to be any convictions for the possession of 1P LSD, and the DEA has never officially mentioned or made any statements about this compound.
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Some countries in Europe have added it to their list of prohibited substances, including:
- The United Kingdom
- The Czech Republic
How to Test 1P-LSD
You only need a small sample to do this effectively, so you aren’t really wasting any money or doses. Just a small sliver of one of your tabs is enough to perform the test.
Substance tests aren’t going to tell you the quality of a tab, but they will tell you if certain compounds are in it or not. The only dangerous compounds that are potent enough to fit on a single blotter paper are LSD and its analogs, NBOMe, or DOMx compounds.
It’s always a good idea to run multiple substance tests for LSD and 1P-LSD. The ideal would be all four mentioned below, but if you’re only going to run one or two, the Ehrlich and Marquis are the most important.
1. Ehrlich Test
This will show you whether the tab contains indole alkaloids (LSD, 1P-LSD, AL-LAD, or other derivatives) or not.
If you only run one test, this is the one.
Place one drop on a small sliver of the tab and wait for it to change color. It should turn purple or dark pink. LSD-25 usually turns right away, while 1P-LSD takes longer (up to 3 minutes).
If there’s no color change, your sample probably doesn’t contain any indole alkaloids and is therefore unsafe to use.
2. Marquis Reagent
The Marquis reagent will identify amphetamines, NBOMe, mescaline, and other substances in your sample. If it turns green, it likely contains NBOMe compounds and should be thrown out.
Follow the chart included in your Marquis test kit for the detection of other compounds.
3. Hofmann Reagent
It’s always a good idea to run two or more tests with different reagents just to make sure. The Hofmann reagent is used to differentiate certain indole alkaloids.
If the sample turns purple, it’s likely an LSD-derivative. If it turns green, it’s 5-MeO-DMT; if yellow, it’s N,N-DMT.
4. Mecke Reagent
The main role of the Mecke reagent is to determine whether there are any opiates in the sample. Since most opiates aren’t strong enough at sub-milligram doses, and the experience of these substances is nothing like LSD, it’s very unlikely for there to be any opiates in the sample.
This test is extra, just to be safe. It’s easy to run the Mecke test to make sure the sample doesn’t contain ultra-potent forms of opiates like fentanyl or kar-fentanyl.
If the Mecke reagent turns blue, it means the sample contains opioids and should therefore be avoided.
Final Thoughts: What’s The Future of 1P-LSD?
This psychoactive substance is virtually identical in its effects to LSD. It’s a prodrug of LSD-25, which means it’s converted into LSD by the liver, which then goes on to produce psychoactive effects.
As more countries find out about this analog, they’ll likely move to place it under the same regulations as LSD.
More liberal countries, like Canada, are unlikely to make this change as laws are already moving towards legalizing LSD anyway. This compound is not dangerous, and there’s no indication it’s going to pose any additional risk to society. We’ll likely see more of this compound in the near future until LSD-25 becomes legal.
it is easier to produce and has a faster onset time than 1P-LSD. When you consider that the two have the same experience, LSD is the slightly better option.
Risk of Adulteration
One of the benefits of it is its lighter legal restrictions. While this psychedelic isn’t technically legal, it isn’t illegal either (in most places). This means it’s easier to find a legit supplier than it is for overtly prohibited compounds. You can order 1P-LSD from reputable names like Sigma Aldrich, or other brand name suppliers, which significantly decreases the chance of adulteration with potentially harmful compounds.
You don’t need to use the black market to buy this stuff. Blackmarket vendors dramatically increase the risk of ordering fake LSD, which often use NBOMe compounds instead — which are dangerous. There have been many deaths associated with this compound in the past.
No matter where you buy 1P-LSD, you should test it using a reagent drug testing kit. Here’s how to do it.
Responsible Use of Psychedelics
As is the case with all psychedelics, it’s critical that you understand how to stay safe with these compounds before you begin. While there isn’t much of a risk in terms of physical side effects, these substances carry the risk of psychological harm.
People with a history of psychosis, schizophrenia, or other mental illness should always consult a psychologist before using psychedelics. In this environment, it’s more likely that LSD-25, psilocybin, or 5-MeO-DMT will be used instead of 1P-LSD due to a lack of clinical research.